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Crystal Cruises 2022 Crystal Serenity Itinerary 2022 VOYAGE NUMBER: OCY220416-27 April 16 May 13 2022 - 27 Days ISTANBUL TO MIAMI  Crystal Serenity Cruise - Exclusive Offers Contact us first before booking your Crystal Serenity Cruise! Don't settle for less - secure the best deal today with our exclusive Crystal discounts. ✨ Save 5% or more on all Crystal sailings ✨ Unbeatable rates available now ✨ Select voyages with no single supplement Book with confidence knowing you're getting the best value. Call or email us today to receive your personalized quote and lock in these limited-time savings! Contact Deluxe Cruises for Personalized Service, Lowest Prices, and Planning Assistance. Call or Email Now!  Accommodations Deluxe Cruises Home |
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| Date | Port | Arrival/Departure | |
| April 2022 | |||
| April 16 2022 | ISTANBUL, TURKEY | PM | - |
| April 17 2022 | ISTANBUL, TURKEY | - | 6:00 PM |
| April 18 2022 | NESSEBAR, BULGARIA | 7:30 AM | 4:00 PM |
| April 19 2022 | ODESSA, UKRAINE | 7:30 AM | 11:00 PM |
| April 20 2022 | CONSTANŢA, ROMANIA | 9:00 AM | 9:00 PM |
| April 21 2022 | CRUISING THE DARDANELLES | - | - |
| April 22 2022 | ATHENS (PIRAEUS), GREECE | 8:00 AM | 6:00 PM |
| April 23 2022 | KATAKOLON, GREECE | 8:00 AM | 3:00 PM |
| April 24 2022 | TAORMINA/GIARDINI NAXOS, ITALY | 7:30 AM | 6:00 PM |
| April 25 2022 | SORRENTO, ITALY | 7:00 AM | 6:00 PM |
| April 26 2022 | ROME (CIVITAVECCHIA), ITALY | 7:00 AM | 9:00 PM |
| April 27 2022 | FLORENCE/PISA (LIVORNO), ITALY | 7:00 AM | 7:00 PM |
| April 28 2022 | MONTE CARLO MONACO | 8:00 AM | - |
| April 29 2022 | MONTE CARLO MONACO | 10:00 AM | 6:00 PM |
| April 30 2022 | CRUISING THE MEDITERRANEAN | - | - |
| May 2022 | |||
| May 01 2022 | CARTAGENA, SPAIN | 8:30 AM | 5:00 PM |
| May 02 2022 | GIBRALTAR, UK | 9:00 AM | 6:00 PM |
| May 03 - May 04 | CRUISING THE ATLANTIC OCEAN | - | - |
| May 05 2022 | PONTA DELGADA, THE AZORES | 8:00 AM | 5:00 PM |
| May 06 - May 09 | CRUISING THE ATLANTIC OCEAN | - | - |
| May 10 2022 | HAMILTON, BERMUDA | 8:00 AM | 6:00 PM |
| May 11 - May 12 | CRUISING THE ATLANTIC OCEAN | - | - |
| May 13 2022 | MIAMI, FLORIDA | 6:30 AM | AM |
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