Crystal luxury cruise itinerary
Crystal Serenity Itinerary 2026
San Diego to San Diego
Review this Crystal Serenity voyage with Deluxe Cruises for itinerary details, suite guidance, preferred rates, special amenities, and personalized luxury cruise planning.
Itinerary at a Glance
December 21 2026-January 8 2027Our journey begins with a couple of days at sea, so make the most of your sumptuous surroundings as we sail south to Topolobampo in Mexico. Here you can venture on the railroad through the Copper Canyon or relax on the beach before our voyage continues to Guaymas. We move on to the seaside town of La Paz, from which there are boat trips to desert islands in a UNESCO biosphere reserve ÔÇô watch out for dolphins and sea lions. Nature-lovers will be wowed by Isla Natividad, too, where elephant seals bask on its beaches. And then itÔÇÖs back via San Diego to the port of Manzanillo, a destination favored by anglers for its marlin-rich waters ÔÇô or to just relax on the beach. Next, we call by Puerto Vallarta, a laidback city known for warmly welcoming members of the LGBTQ+ community. At Mazatl├Ãn, dine on seafood, admire the French baroque architecture, and sit on the sands in the shade of the palm trees. Cabo San Lucas is the place to watch whales put on a magnificent show in the early months of the year, when they visit to feed and breed. All too soon, itÔÇÖs time to return to San Diego once more.
Quick, low-cost quotes
Contact Deluxe Cruises before you reserve
Before making a decision for your Crystal Serenity cruise, contact Deluxe Cruises for preferred pricing, special amenities, suite advice, and personalized service.
Why not get the best deal at the outset? Our cruise advisors can help compare the itinerary, suite category, sailing date, inclusions, and current offers before you book.
Contact a Crystal cruise specialist for detailed information about this Crystal Serenity sailing and current Deluxe Cruises offers.
Our journey begins with a couple of days at sea, so make the most of your sumptuous surroundings as we sail south to Topolobampo in Mexico. Here you can venture on the railroad through the Copper Canyon or relax on the beach before our voyage continues to Guaymas. We move on to the seaside town of La Paz, from which there are boat trips to desert islands in a UNESCO biosphere reserve – watch out for dolphins and sea lions. Nature-lovers will be wowed by Isla Natividad, too, where elephant seals bask on its beaches. And then it’s back via San Diego to the port of Manzanillo, a destination favored by anglers for its marlin-rich waters – or to just relax on the beach. Next, we call by Puerto Vallarta, a laidback city known for warmly welcoming members of the LGBTQ+ community. At Mazatlán, dine on seafood, admire the French baroque architecture, and sit on the sands in the shade of the palm trees. Cabo San Lucas is the place to watch whales put on a magnificent show in the early months of the year, when they visit to feed and breed. All too soon, it’s time to return to San Diego once more.
Quick, low-cost quotes
Contact Deluxe Cruises before you reserve
Before making a decision for your Crystal Serenity cruise, contact Deluxe Cruises for preferred pricing, special amenities, suite advice, and personalized service.
Why not get the best deal at the outset? Our cruise advisors can help compare the itinerary, suite category, sailing date, inclusions, and current offers before you book.
Contact a Crystal cruise specialist for detailed information about this Crystal Serenity sailing and current Deluxe Cruises offers.